Alopecia dating site

The currently preferred treatment for androgenetic alopecia is topically administered 2 percent minoxidil.69 Minoxidil appears to affect the hair follicle in three ways: it increases the length of time follicles spend in anagen, it “wakes up” follicles that are in catagen, and it enlarges the actual follicles.The mechanism by which minoxidil effects these changes is not known.

Corticosteroids and other agents are typically used in women with alopecia areata.

Telogen effluvium is often a self-limited disorder.

Because alopecia can be devastating to women, management should include an assessment for psychologic effects.

Although alopecia can occur anywhere on the body, it is most distressing when it affects the scalp.

Women with androgenetic alopecia do not have higher levels of circulating androgens.

However, they have been found to have higher levels of 5α-reductase (which converts testosterone to dihydrotestosterone), more androgen receptors, and lower levels of cytochrome P450 (which converts testosterone to estrogen).6Most women with androgenetic alopecia have normal menses, normal fertility, and normal endocrine function, including gender-appropriate levels of circulating androgens.Vellus hairs enlarge and are converted to terminal hairs. In a randomized, controlled, double-blind clinical trial involving 550 women 18 to 45 years of age, treatment with 2 percent minoxidil solution resulted in a higher hair count compared with placebo.10 [Evidence label A, randomized controlled trial] In another study,11 50 percent of women treated with 2 percent minoxidil had at least minimal hair regrowth, and 13 percent had moderate regrowth.No significantly increased benefit has been shown for the 5 percent minoxidil solution compared with the 2 percent solution.8 The U. Food and Drug Administration (FDA) has labeled topically administered minoxidil for the treatment of androgenetic alopecia.Approximately 60 hairs are grasped between the thumb and the index and middle fingers. A negative test (six or fewer hairs obtained) indicates normal shedding, whereas a positive test (more than six hairs obtained) indicates a process of active hair shedding. J Am Acad Dermatol 1996;35(3 pt 1):465–9Adapted with permission from Healey PM, Jacobson EJ. However, visible hair loss occurs in approximately one half of all persons by the age of 50 years8 Hair follicles contain androgen receptors.Patients should not shampoo their hair 24 hours before the test is performed.4If the diagnosis is not clear based on the history and physical examination, selected laboratory tests and, occasionally, punch biopsy may be indicated. Philadelphia: Saunders, 208–11, with additional information from Drake LA, Dinehart SM, Farmer ER, Goltz RW, Graham GF, Hordinsky MK, et al. In the presence of androgens, genes that shorten the anagen phase are activated, and hair follicles shrink or become miniaturized.Minoxidil is listed as a pregnancy category C drug.

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